منابع مشابه
The Role of Interleukin-1 Genotype in the Association between Coronary Heart Disease and Periodontitis in a Syrian Population
Objective. To determine whether differences exist between periodontitis subjects with and without Coronary Heart Disease (CHD) in a Syrian population in the distribution of IL-1 alleles at positions IL-1α+4845, IL-1β+3954, IL-1β-511, and IL-1RN VNTR. Background. The role of Interleukin-1 genes in the association between periodontitis and CHD has been demonstrated in previous studies. No study h...
متن کاملAssociation of interleukin-1 polymorphisms with periodontitis in Down syndrome.
This study examined the association of IL1 genetic polymorphisms (IL-1A +4845, IL-1B +3954 & IL-1RN +2018) with periodontal disease status of Down syndrome (DS) individuals. Fifty-four DS patients (18-56 yr, 48.15% male, 77.78% Caucasians) were recruited from the Georgia Regional Hospital (GRH) health care system. Two comparable groups (71 mentally retarded patients and 87 control subjects) wer...
متن کاملassociation of interleukin-1 α (–889) gene polymorphism in patients with generalized aggressive and chronic periodontitis
background: there is a strong evidence that genetic as well as environmental factors affect the age of onset, severity and lifetime risk of developing periodontitis. the objective of the present study was to compare and to evaluate the association between interleukin (il)-1α(-889) and gene polymorphisms in patients with generalized aggressive periodontitis, chronic periodontitis and healthy con...
متن کاملInterleukin 1β (+3954; −511) Genotype Polymorphism and its Association with Severe Chronic Generalized Periodontitis in the Malaysian Population
INTRODUCTION Single-nucleotide polymorphisms (SNPs) in interleukin 1β (IL-1β) gene have been known to be associated with increased susceptibility to chronic periodontitis among various ethnic populations. SNPs are more commonly observed at loci + 3954 and - 511. The aim of this study was to evaluate the role of IL-1β gene polymorphism at loci +3954 and - 511, and its association with severe chr...
متن کاملInterleukin - 1 Polymorphisms And Chronic Periodontitis In A Rural Kenyan Population
Susceptibility to Chronic periodontitis (CP) has been associated with genetic polymorphisms in the proinflammatory cytokine, interleukin-1 (IL-1A and IL-1B) isoforms but little is known about their role in rural Africans. Therefore, the aim of this study was to resolve the association between genetic polymorphisms in IL1A and IL-1B isoforms and chronic periodontitis in the Taita people of Kenya...
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ژورنال
عنوان ژورنال: Archivum Immunologiae et Therapiae Experimentalis
سال: 2019
ISSN: 0004-069X,1661-4917
DOI: 10.1007/s00005-019-00555-4